"This disease manifests itself in mysterious ways... I've tentatively named it 'Stigma'." -Lloyd Wilkens

Stigma is a virus that was created accidentally by Markus Vaughn and Lloyd Wilkens. It was used as a biological weapon after the leader of Parnassus, Master Vakhushti, obtained it from Prof Wilkens. It comes in six strains, each named after a body part it resembles or attacks.

It has been known that Stigma stores its genetic information in a film-like structure, unlike other biological pathogens, and that it cannot grow without culurium, an alloy found in Culurama. This would explain why all of the initial Stigma victims are those who have used products involving culurium.

Over the events of New Blood, Stigma mutates and eventually becomes more infectious, even able to grow without the need for culurium.

The Birth of StigmaEdit

Six years prior to the events of New Blood, Markus was working on lab mice with Prof Wilkens, when he noticed that one of them was unusual. While excising a tumor from that lab mouse, Markus accidentally let Stigma come into contact with artificial blood, and it began growing extremely quickly. Lloyd insisted on continuing research on the new pathogen, thus spurring Markus to leave for Alaska.

Cheir (The hand)Edit

Cheir is the New Blood equivalent to Second Opinion's Kyriaki. With its sharp shape, it creates lacerations, gashes, and tumors (in certain mutations) in order to shut the organ down. Professor Wilkens is the first patient operated on with Cheir.

Soma (The body)Edit

Soma appears as a core covered in viscous fluid that releases hardening tissue and tumors. When under threat, it will also create a copy of itself that produces a large amount of tissue if left untouched for some time. A patient from Texas - who had Q-Heme artificial blood infused from a previous operation - is the first known victim of Soma.

Ops (The eye)Edit

Ops acts as a sphere in the middle of an organ surrounded by tissue, while two outside bodies shoot it nutrients. The nutrients allow for it to commence reactions that require energy in order to damage vitals, like causing tumors to burst. Samantha Young, a patient on Wish Come True: Miracle Surgery is the first known case of Ops, which even Leonardo Bello couldn't stop.

Onyx (The claw)Edit

Onyx hides in the organ it attacks at first. If it takes too long to find the Onyx, or if a copy is excised, it will attack, creating lacerations. When under threat, it will also release a toxin that causes vital damage, though in the process it renders itself and its copies visible. While Dr. Vaughn, Dr. Blaylock, and Elena are held captive, they are forced to operate on Onyx twice.

Brachion (The arm)Edit

Brachion releases toxin into the victim through use of extended arms and grapplers that attach itself to the affected organ. Dr. Vaughn, Dr. Blaylock, and Elena first operate on Brachion after they escaped from Kidman's captivity and before they went to Culuruma.

Cardia (The heart)Edit

Cardia first tries to shut down the heart by covering it in a membrane, and upon reaching red sections of the membrane will harm the patient and cause the patient's vitals to permanently drop. After the membrane is completely removed, it will then try to attack by creating lacerations and releasing bomb-like tumors it detonates with a "ripple". Master Vakhushti created this one-of-a-kind Stigma to suppress his malignant diencephalic sclerosis, but in doing so he suffered delirium, becoming twisted and sadistic.

    vde Trauma Center series
Games Under the KnifeSecond OpinionNew BloodUnder the Knife 2Trauma Team
Characters Derek StilesAngie ThompsonNaomi KimishimaMarkus VaughnValerie BlaylockElena SalazarCR-S01Maria TorresHank FreebirdTomoe TachibanaGabriel Cunningham
Fields SurgeryFirst ResponseOrthopedicsEndoscopyDiagnosisForensics
Organizations Caduceus InternationalDelphiEidoth PharmaceuticalsHumaniParnassusAcropolis PharmaceuticalHands of AsclepiusResurgam First CareCumberland Institute of Forensic Medicine
GUILT KyriakiDefteraTritiTetartiPemptiParaskeviSavatoBlissPGS
Stigma CheirSomaOpsOnyxBrachionCardia
Neo-GUILT NousBythosSigeAletheia
Other Rosalia Virus