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"Kenneth said they used human subjects in their research. In order to culture the GUILT samples effectively, they needed young tissue. ...Children." -Robert Hoffman

To facilitate the development of GUILT strains, Delphi kidnapped children from across the world with a suitable genetic makeup. These children are called "Sinners" to befit their twisted ideology, and are kept in a barely-conscious state as their GUILT strains are tested and developed. The same fate would have befallen Angie if her father had not chosen to work with Delphi in exchange for her safety.

The age range of Sinners is left ambiguous. Under the Knife portrays them as very young children around 10, while Under the Knife 2 implies that young teens could also be used. Under the Knife 2 also introduces the concept of adults being used as Sinners, although this may be attributed to different techniques used by the Delphi Remnants.

Name GUILT
Unnamed boy Immature Kyriaki and Mature Kyriaki
Unnamed boy Deftera
Unnamed girl Triti
Unnamed boy Mature Tetarti
Emilio Juarez Pempti
Unnamed girl Paraskevi
Unnamed boy Immature Savato, Blue Savato and Savato
Heinrich von Raitenau Mutated B Tetarti
Karl Immature Kyriaki, Mature Kyriaki and Queen Kyriaki
Christine Mutated Pempti
Adam Bliss

UtK2 Sinners[]

Nous, Sige, Bythos, and Aletheia[]

While no Sinners for Nous, Sige, Bythos and Aletheia have been shown, it is possible that Reina Mayuzumi is an Aletheia Sinner, since she was the only one infected with it. However, it is possible that they don't have Sinners, as the Neo-GUILT were created separately from the original GUILT made by Delphi.

Trivia[]

Judging from the letters received by Derek and Angie at the end of Under the Knife, the Sinners for the initial seven strains of GUILT could be of the following nationalities:

  • British
  • German
  • French
  • Chinese
  • Mexican (Emilio)
  • Russian
  • Italian
Trauma Center: Under the Knife and Trauma Center: Second Opinion
Characters
Caduceus Derek StilesAngela ThompsonRobert HoffmanSidney KasalTyler ChaseVictor NiguelCybil MyersStephen ClarksLeslie Sears
Delphi AdamKenneth BlackwellNozomi WeaverNavelOwen
Patients Linda ReidAmy ChaseSinners
Others Greg KasalMary FultonRichard AndersonLangston Miller
For minor characters, see: Minor Characters
Episodes
Chapter 1: Dr. Stiles PrologueStandard ProcedureStandard Procedure 2/Learning the RopesA FarewellNurse AngieSinging the BluesA Real DoctorDownpourLife or Death
Chapter 2: The Healing Touch Dormant AbilityMaster SurgeryStriving for AsclepiusAwakeningPaying the PriceJust Let Me DieReasons WhyReconciliationPlease Let Me LiveCaduceusFor Everyone's Sake/For the Greater Good
Chapter 3: Caduceus New BeginningsGUILTThe Darkness WithinSomething PreciousInternational ConferenceAn Explosive PatientFootfalls of TerrorMiracle at 9,800ft/Caduceus on a PlaneDeserted VillageForbidden Knowledge/Pandora's Box
Chapter 4: Bio Terror Hope Under AttackRace for the CureNothing to Do but WaitStepping UpForeboding CluesTaking a First Step/The First StepMedical ResearchThe Next StepNew Laser Technology/ProgressDoctors' Struggle/Prolonged StruggleIncurable Disease
Chapter 5: It Never Ends Caduceus in ActionUnder the KnifeShifting GUILTGUILT EvolvesInfiltrationInfectionDelphiDevil/A DevilDeath Awaits All
Chapter 6: Original Sin (UtK) Delphi HQFirst SinSecond SinThird SinFourth SinFifth SinSixth SinFinal SinAdamEpilogue
Chapter 6: Dark Gospel (SO) An InvitationCaduceus EuropeRelapseSecond OpinionOriginal SinThe Future of GUILTFallen HeroesVulnerabilityEpilogue
Z-Episodes (SO) From OverseasMiraclePursuitTransplantSayonara
X missions X-1: KyriakiX-2: DefteraX-3: TritiX-4: TetartiX-5: PemptiX-6: ParaskeviX-7: Savato
Trauma Center: Under the Knife 2
Characters
Caduceus Derek StilesAngela ThompsonAdel TulbaRobert HoffmanSidney KasalTyler ChaseVictor NiguelStephen ClarksLeslie Sears
Delphi Heinrich von RaitenauKarl/Christine von Raitenau
Patients Linda ReidEmilio Juarez
Others Heather RossGreg KasalCybil MyersMary FultonKenneth BlackwellPatrick MercerReina Mayuzumi
For minor characters, see: Minor Characters
Episodes
Chapter 1: Doctor in a Foreign Land Refugee CampMaster SurgeonNovice MistakeHidden PerilCivil WarFeverLeaving Africa
Chapter 2: Return to Caduceus Alone in the ORPGSTo Live OnOminous CloudsSinnerRebirth
Chapter 3: Onset TemptationPrime TimeFor the FutureElysiumFamiliar FacesGUILT ReturnsOverconfidence
Chapter 4: Relearning the Ropes CollapseLosing FaithRehabilitationHope HospitalA Rough NightVisitorBlackwellDesperate PleaThe Touch
Chapter 5: Unnatural Abilities The HOARetaliationNew HeroesAbductionThe TraceThe CarrierShift in Power
Chapter 6: Lineage A New AllyAnathemaWidespread FearBackfireLord of PlaguesImprovisingTragedy
Chapter 7: Illusion Secret PatientTainted MedicineTruth UnveiledDream's EndHall of ShadowsThe AltarMother of SinsEpilogue
X missions X-1: KyriakiX-2: TetartiX-3: PemptiX-4: NousX-5: BythosX-6: SigeX-7: Aletheia
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